. Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s). Biochemistry. 2003 Jan 14;42(1):137-44. PubMed.


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  1. Interesting study that optimizes an in vitro gamma-secretase cleavage assay. While the results have been reported elsewhere mostly from intact cells, this is a thorough study with important confirmations using a different system.

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