. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 2000 Sep 7;407(6800):48-54. PubMed.


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  1. A key paper accelerating the subsequent discovery of the members in the gamma-secretase complex.

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  1. Nicastrin—A DAPper Role in γ-Secretase