. Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis. Neurochem Res. 2006 Oct;31(10):1263-9. PubMed.


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  1. EGCG also has neuroprotective effects on Alzheimer disease transgenic mouse models of amyloidosis, by increasing ADAM10 and the non-amyloidogenic pathway.


    . ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. J Biol Chem. 2006 Jun 16;281(24):16419-27. PubMed.

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