. Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance. Nature. 2024 Feb 28; PubMed.

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  1. Fantastic work by both groups. The work by Jonathan Kipnis and colleagues could provide an additional explanation for why we saw plaque clearance in APP/PS1 mice after optogenetic rescue of slow waves during sleep.

    References:

    . Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model. Mol Neurodegener. 2023 Dec 1;18(1):93. PubMed.

    View all comments by Ksenia Kastanenka

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