. Neurofilament protein in cerebrospinal fluid: a marker of white matter changes. J Neurosci Res. 2001 Nov 1;66(3):510-6. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD
(22)
415 ± 147
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
CNC
(20)
522 ± 141
pg/mL
ELISA;
Innotest;
Innogenetics
NFL
(CSF)
AD
(22)
569 ± 308
pg/mL
ELISA;
Other/Not Specified;
In-house
McKhann et al., 1984
NFL
(CSF)
CTRL-
CNC
(20)
156 ± 66
pg/mL
ELISA;
Other/Not Specified;
In-house
albumin ratio
(CSF/Blood)
AD
(22)
6.2 ± 1.5
(CSF mg/L)/(Serum g/L)
Nephelometry;
Other/Not Specified;
CSL Behring LLC
McKhann et al., 1984
albumin ratio
(CSF/Blood)
CTRL-
CNC
(20)
6.5 ± 2.5
(CSF mg/L)/(Serum g/L)
Nephelometry;
Other/Not Specified;
CSL Behring LLC
tau-total
(CSF)
AD
(22)
725 ± 389
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(20)
350 ± 187
pg/mL
ELISA;
Innotest;
Innogenetics

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