. The National Institute on Aging and Alzheimer's Association research framework: A commentary from the Cochrane Dementia and Cognitive Improvement Group. Alzheimers Dement. 2019 Jan;15(1):179-181. PubMed.


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  1. This commentary is a clear and important critique of the attempt to redefine Alzheimer's disease in the "NIA-AA Research Framework." As a senior colleague stated when I showed it to him: "It is rare that anything is achieved by the assertion of authority in science. But folk keep doing it."

    There are a number of other interesting commentaries on this topic in the same issue of Alzheimer's & Dementia in a "Special Topic Section: Responses to the NIA-AA Research Framework." The social, financial, and research impacts of acceptance of the NIA-AA Research Framework would be significant, so it is important that people involved in AD research appreciate the arguments.

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