. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. Science. 1998 Dec 4;282(5395):1914-7. PubMed.


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  1. This is an interesting paper as it offers a mechanism by which tau mutations may cause neuronal dysfunction in FTDP-1.

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This paper appears in the following:


  1. What FTDP-17 Mutations Do
  2. Mutant Tau Stiffens Axon Cytoskeleton Near Soma


  1. MAPT R406W