. Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42. J Biol Chem. 1998 Aug 14;273(33):21153-60. PubMed.


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  1. It is challengeable and interesting that dimeric formation may be coupled with truncation of PS2.

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