. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules. Cell Mol Biol (Noisy-le-grand). 1998 Nov;44(7):1117-27. PubMed.


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  1. This paper suggests that in AD tau is modified by AGE and this modifications result in functional abnormalities of the microtubules system of the cell. An interesting observation. If replicated it going to be important for AD.

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