. Mitochondrial DNA mutations in Alzheimer's disease. Biochem Biophys Res Commun. 1997 Dec 18;241(2):221-5. PubMed.


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  1. An important area with a number of findings of uncertain value. A recent paper in PNAS (Hirano et al., 1997, 94:14894-14899) indicates that some of the mt mutations previously described may be due to PCR amplification of nuclear mt DNA pseudogenes consequent to design of the PCR primers.


    . Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14894-9. PubMed.

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