. Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis. EMBO J. 2018 Jun 1;37(11) Epub 2018 May 15 PubMed.

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Research Models

  1. Tardp LCDmut
  2. Tardp_RRM2mut
  3. Tardbp Q331K Knock-In