. Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4986-91. PubMed.


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  1. A recent paper in Human Molecular Genetics also observed that TARDBPl compensates for the loss of TARDBP.


    . Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Hum Mol Genet. 2013 Jun 15;22(12):2376-86. PubMed.

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  1. Paper Alert: Zebrafish Say TDP-43 Causes ALS by Loss of Function