. Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement. Brain Res. 1998 Mar 23;787(2):259-68. PubMed.


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  1. Estrogen could be a potent drug to treat dementia. It is important to know its mode of action in brain. This paper examined the changes of expression of trkA, BDNF, NGF genes. The authors study these interesting molecules as the second regulator to response estrogen.

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