. The level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimer's disease. Neuroreport. 1997 Dec 22;8(18):3961-3. PubMed.


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  1. A correlation of 0.44 produces an R squared of 0.19, meaning that the correlation of CSF tau with NFT scores accounts for only 19% of the variability in the NFT data. The magnitide of the correlation also suggests that there may be significant overlap between AD and control values for CSF tau.

  2. To further the search for concrete diagnostic tools, any study is essentially welcome. This study is one of such trials.

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