. Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. J Biol Chem. 2000 Nov 3;275(44):34393-8. PubMed.


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  1. It is no doubt to see an interaction of alpha -Syn with the lipid fraction because alpha-Syn has been identified as a hydrophobic synaptic component. The urgent issue to know may be in the next step for alpha-Syn.

  2. Important contribution to understanding synuclein biology.

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