. Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease. Sci Transl Med. 2019 Aug 28;11(507) PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
sTREM2
(CSF)
AD
(66)
4608 ± 2201
pg/mL
Electrochemiluminescence;
Other/Not Specified;
In-house
McKhann et al., 1984
sTREM2
(CSF)
CTRL-
CNC
(100)
3762 ± 1841
pg/mL
Electrochemiluminescence;
Other/Not Specified;
In-house

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : sTREM2 (CSF)
  2. CTRL vs AD : sTREM2 (CSF)