. Identification of a novel family of presenilin homologues. Hum Mol Genet. 2002 May 1;11(9):1037-44. PubMed.


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  1. While the homology between these proteins and PS1 and PS2 is not great, their importance is that their occurrence suggests there may be many other regulated membrance cleavage pathways and detailed comparisons may also give mechanistic insights into the cleavge events.

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