. Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease. Ann Neurol. 1998 Mar;43(3):303-10. PubMed.


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  1. This is consistent with other studies suggesting the significance of APO E may not be through an action on the neuropil.

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  1. ApoE and Brain Networks—The Anatomy of a Risk Factor