Ghebremedhin E, Schultz C, Braak E, Braak H. High frequency of apolipoprotein E epsilon4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes. Exp Neurol. 1998 Sep;153(1):152-5. PubMed.

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  1. The results of this study are consistent with the earlier onset of clinically defined AD in ApoE4+ individuals.

    View all comments by Paul Coleman

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