Tambini MD, Yao W, D'Adamio L. Facilitation of glutamate, but not GABA, release in Familial Alzheimer's APP mutant Knock-in rats with increased β-cleavage of APP. Aging Cell. 2019 Dec;18(6):e13033. Epub 2019 Sep 9 PubMed.

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Research Models

  1. App knock-in (humanized Aβ)
  2. App knock‐in (Swedish mutation and humanized Aβ)
  3. App knock‐in (Icelandic mutation and humanized Aβ)
  4. Trem2 R47H knock-in
  5. Psen1 L435F knock-in

News

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Mutations