. Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S. J Neurosci. 2010 Feb 3;30(5):1788-97. PubMed.


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  1. At PDOnline Research, Zhenyu Yue of Mount Sinai School of Medicine discusses two new BAC Lrrk2 mouse models, recently published in Journal of Neuroscience.

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Research Models

  1. LRRK2 G2019S Mouse (BAC Tg)