. E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. J Biol Chem. 2000 Apr 21;275(16):11553-60. PubMed.


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  1. This is one of the interesting papers in AD. Several lines of knowledge on molecules such as p53 or other caspases involved in the well-known cellular oncogenic or pathological cascades are welcome in AD-related cell death because of simple interest and for the background information this brings to the AD field.

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