. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med. 2003 May;9(5):589-95. PubMed.


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  1. These papers provide support for Parkinson's disease therapies and a basis for understanding L-DOPA's iatrogenic effects. It is curious that the GDNF recovery of function proceeded even as brain deterioration progressed.

    View all comments by Ruth Perez

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