. Deletion of exons 9 and 10 of the Presenilin 1 gene in a patient with Early-onset Alzheimer Disease generates longer amyloid seeds. Neurobiol Dis. 2017 Aug;104:97-103. Epub 2017 Apr 28 PubMed.

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Mutations

  1. PSEN1 S290W;S291_R377del (Δ9-10 )