Morris EJ, Keramaris E, Rideout HJ, Slack RS, Dyson NJ, Stefanis L, Park DS. Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. J Neurosci. 2001 Jul 15;21(14):5017-26. PubMed.

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- Inez Vincent
- Posted: 04 Jul 2002
This report is a continuation of a series of papers in which Dr Park and his colleagues attempt to unravel the intricacies of the cell cycle driven mechanism of neuronal apoptosis. The involvement of DNA damage in this process is especially important in light of the age-associate neurodegenerative diseases, because cumulative DNA damage is an established hallmark of brain aging.

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