. Clusterin Levels in Plasma Predict Cognitive Decline and Progression to Alzheimer's Disease. J Alzheimers Dis. 2015;46(4):1103-10. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD
(107)
432 ± 182
pg/mL
ELISA;
Innotest;
Fujirebio
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
CNC
(67)
977 ± 208
pg/mL
ELISA;
Innotest;
Fujirebio
Aβ42
(CSF)
MCI-AD
(19)
416 ± 121
pg/mL
ELISA;
Innotest;
Fujirebio
Petersen et al., 1999; McKhann et al., 1984
Aβ42
(CSF)
MCI-Stable
(31)
710 ± 303
pg/mL
ELISA;
Innotest;
Fujirebio
Petersen et al., 1999
tau-phospho
(CSF)
AD
(107)
90 ± 41
pg/mL
ELISA;
Innotest;
Fujirebio
McKhann et al., 1984
tau-phospho
(CSF)
CTRL-
CNC
(67)
43 ± 15
pg/mL
ELISA;
Innotest;
Fujirebio
tau-phospho
(CSF)
MCI-AD
(19)
91 ± 53
pg/mL
ELISA;
Innotest;
Fujirebio
Petersen et al., 1999; McKhann et al., 1984
tau-phospho
(CSF)
MCI-Stable
(31)
62 ± 39
pg/mL
ELISA;
Innotest;
Fujirebio
Petersen et al., 1999
tau-total
(CSF)
AD
(107)
772 ± 465
pg/mL
ELISA;
Innotest;
Fujirebio
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(67)
243 ± 102
pg/mL
ELISA;
Innotest;
Fujirebio
tau-total
(CSF)
MCI-AD
(19)
771 ± 704
pg/mL
ELISA;
Innotest;
Fujirebio
Petersen et al., 1999; McKhann et al., 1984
tau-total
(CSF)
MCI-Stable
(31)
401 ± 325
pg/mL
ELISA;
Innotest;
Fujirebio
Petersen et al., 1999

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