Kvartsberg H, Portelius E, Andreasson U, Brinkmalm G, Hellwig K, Lelental N, Kornhuber J, Hansson O, Minthon L, Spitzer P, Maler JM, Zetterberg H, Blennow K, Lewczuk P. Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls. Alzheimers Res Ther. 2015;7(1):40. Epub 2015 Jul 1 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
neurogranin
(CSF)		 AD
(25)		 661.5 ± 200.5
pg/mL §		 Electrochemiluminescence;
In-house;
In-house		 McKhann et al., 1984
neurogranin
(CSF)		 CTRL-
CNC
(20)		 359.6 ± 188.9
pg/mL §		 Electrochemiluminescence;
In-house;
In-house
neurogranin
(Plasma)		 AD
(25)		 61771 ± 75640
pg/mL §		 Electrochemiluminescence;
In-house;
In-house		 McKhann et al., 1984
neurogranin
(Plasma)		 CTRL-
CNC
(20)		 83717 ± 100976
pg/mL §		 Electrochemiluminescence;
In-house;
In-house

§ Data supplied to Alzforum by author

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