. Cerebrospinal fluid neuron-specific enolase: a further marker of Alzheimer's disease?. Funct Neurol. 2008 Apr-Jun;23(2):93-6. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD
(76)
413.8 ± 163.7
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
CNC
(30)
914.4 ± 277.1
pg/mL
ELISA;
Innotest;
Innogenetics
NSE
(CSF)
AD
(76)
15.1 ± 9.9
ng/mL
Radio Immunoassay;
Other/Not Specified;
CIS Bio International S.A.
McKhann et al., 1984
NSE
(CSF)
CTRL-
CNC
(30)
8.3 ± 3.5
ng/mL
Radio Immunoassay;
Other/Not Specified;
CIS Bio International S.A.
tau-total
(CSF)
AD
(76)
607.9 ± 372.3
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(30)
176.6 ± 43.9
pg/mL
ELISA;
Innotest;
Innogenetics

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : Aβ42 (CSF)
  2. AD vs CTRL : tau-total (CSF)
  3. AD vs CTRL : NSE (CSF)