Kim HJ, Lim TS, Lee SM, Kim TS, Kim Y, An YS, Youn YC, Park SA, Chang J, Moon SY. Cerebrospinal Fluid Levels of β-Amyloid 40 and β-Amyloid 42 are Proportionately Decreased in Amyloid Positron-Emission Tomography Negative Idiopathic Normal-Pressure Hydrocephalus Patients. J Clin Neurol. 2019 Jul;15(3):353-359. PubMed.
AlzBiomarker Database
Meta-Analysis
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ40 (CSF) |
AD (10) |
5462.5 ± 2192.2 pg/mL |
ELISA; Innotest; Fujirebio |
McKhann et al., 1984 |
| Aβ40 (CSF) |
NPH (10) |
5504 ± 2867.1 pg/mL |
ELISA; Innotest; Fujirebio |
|
| Aβ42 (CSF) |
AD (10) |
391.8 ± 120.2 pg/mL |
ELISA; Innotest; Fujirebio |
McKhann et al., 1984 |
| Aβ42 (CSF) |
NPH (10) |
892.8 ± 311.4 pg/mL |
ELISA; Innotest; Fujirebio |
|
| tau-p181 (CSF) |
AD (10) |
78.1 ± 30.6 pg/mL |
ELISA; Innotest; Fujirebio |
McKhann et al., 1984 |
| tau-p181 (CSF) |
NPH (10) |
30.4 ± 9.5 pg/mL |
ELISA; Innotest; Fujirebio |
|
| tau-total (CSF) |
AD (10) |
720.7 ± 220 pg/mL |
ELISA; Innotest; Fujirebio |
McKhann et al., 1984 |
| tau-total (CSF) |
NPH (10) |
238.9 ± 103.7 pg/mL |
ELISA; Innotest; Fujirebio |
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