. The Aβ aggregation modulator MRZ-99030 prevents and even reverses synaptotoxic effects of Aβ1-42 on LTP even following serial dilution to a 500:1 stoichiometric excess of Aβ1-42, suggesting a beneficial prion-like seeding mechanism. Neuropharmacology. 2020 Nov 15;179:108267. Epub 2020 Aug 3 PubMed.

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