Hirano M, Shtilbans A, Mayeux R, Davidson MM, Dimauro S, Knowles JA, Schon EA. Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14894-9. PubMed.
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Banner Research Institute
This is an important caution to studies of mt DNA mutations in AD (as well as to other studies using PCR).
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