. APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease. 2023 Aug 16 10.1101/2023.08.14.552850 (version 1) bioRxiv.

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Mutations

  1. APOE C130R (ApoE4)
  2. APOE R176C (ApoE2)