Vanderstichele H, De Vreese K, Blennow K, Andreasen N, Sindic C, Ivanoiu A, Hampel H, Bürger K, Parnetti L, Lanari A, Padovani A, DiLuca M, Bläser M, Olsson AO, Pottel H, Hulstaert F, Vanmechelen E. Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies. Clin Chem Lab Med. 2006;44(12):1472-80. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ42
(CSF)		 AD
(94)		 403.3 ± 160.8
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
Aβ42
(CSF)		 CTRL-
Other Controls
(60)		 719.2 ± 303.2
pg/mL		 ELISA;
Innotest;
Innogenetics
Aβ42
(CSF)		 DLB
(60)		 454.8 ± 177.1
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith et al., 1996
tau-p181
(CSF)		 AD
(94)		 84.5 ± 38.1
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-p181
(CSF)		 CTRL-
Other Controls
(60)		 44.2 ± 16.2
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-p181
(CSF)		 DLB
(60)		 49.8 ± 22.5
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith et al., 1996
tau-total
(CSF)		 AD
(94)		 648.8 ± 342.1
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-total
(CSF)		 CTRL-
Other Controls
(60)		 226.6 ± 125.2
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-total
(CSF)		 DLB
(60)		 326.8 ± 241.7
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith et al., 1996

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : Aβ42 (CSF)
  2. CTRL vs AD : Aβ42 (CSF)
  3. DLB vs AD : Aβ42 (CSF)
  4. AD vs CTRL : tau-p181 (CSF)
  5. CTRL vs AD : tau-p181 (CSF)
  6. DLB vs AD : tau-p181 (CSF)
  7. AD vs CTRL : tau-total (CSF)
  8. CTRL vs AD : tau-total (CSF)
  9. DLB vs AD : tau-total (CSF)