. Amino-truncated beta-amyloid42 peptides in cerebrospinal fluid and prediction of progression of mild cognitive impairment. Clin Chem. 2005 Sep;51(9):1650-60. Epub 2005 Jul 14 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD
(66)
392 ± 141
ng/L §
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
CNC
(29)
832 ± 191
ng/L §
ELISA;
Innotest;
Innogenetics
Aβ42
(CSF)
DLB
(15)
485 ± 204
ng/L §
ELISA;
Innotest;
Innogenetics
McKeith et al., 1996
Aβ42
(CSF)
MCI-AD
(15)
579 ± 263
ng/L §
ELISA;
Innotest;
Innogenetics
Petersen et al., 1999; McKhann et al., 1984
Aβ42
(CSF)
MCI-Stable
(26)
633 ± 226
ng/L §
ELISA;
Innotest;
Innogenetics
Petersen et al., 1999
Aβ42
(CSF)
PD
(15)
673 ± 123
ng/L §
ELISA;
Innotest;
Innogenetics
Hughes et al., 1992
tau-p181
(CSF)
AD
(65)
197 ± 81
ng/L §
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-p181
(CSF)
CTRL-
CNC
(29)
86 ± 44
ng/L §
ELISA;
Innotest;
Innogenetics
tau-p181
(CSF)
DLB
(15)
110 ± 38
ng/L §
ELISA;
Innotest;
Innogenetics
McKeith et al., 1996
tau-p181
(CSF)
MCI-AD
(15)
191 ± 88
ng/L §
ELISA;
Innotest;
Innogenetics
Petersen et al., 1999; McKhann et al., 1984
tau-p181
(CSF)
MCI-Stable
(26)
78 ± 32
ng/L §
ELISA;
Innotest;
Innogenetics
Petersen et al., 1999
tau-p181
(CSF)
PD
(15)
79 ± 19
ng/L §
ELISA;
Innotest;
Innogenetics
Hughes et al., 1992
tau-total
(CSF)
AD
(66)
394 ± 159
ng/L §
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(29)
240 ± 103
ng/L §
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
DLB
(15)
218 ± 107
ng/L §
ELISA;
Innotest;
Innogenetics
McKeith et al., 1996
tau-total
(CSF)
MCI-AD
(15)
374 ± 131
ng/L §
ELISA;
Innotest;
Innogenetics
Petersen et al., 1999; McKhann et al., 1984
tau-total
(CSF)
MCI-Stable
(26)
179 ± 79
ng/L §
ELISA;
Innotest;
Innogenetics
Petersen et al., 1999
tau-total
(CSF)
PD
(15)
208 ± 52
ng/L §
ELISA;
Innotest;
Innogenetics
Hughes et al., 1992

§ Data supplied to Alzforum by author

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