. Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau. J Neurosci Res. 1997 Apr 15;48(2):128-32. PubMed.

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Comments

  1. Noteworthy.

  2. Noteworthy

  3. This antibody recognizes a folded conformation of tau containing amino acids 2-10 and 312-342. We have used it successfully to detect misfolded tau in mouse models of tauopathy using array tomography, a relatively new imaging technique (Kopeikina et al., 2013).

    References:

    . Synaptic alterations in the rTg4510 mouse model of tauopathy. J Comp Neurol. 2012 Oct 10; PubMed.

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