. Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice. Neurobiol Dis. 2005 Dec;20(3):814-22. PubMed.


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  1. These results fit well with the the tau/APP syngergy observed in the human brain (Delacourte et al., 2002).


    . Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease. Neurology. 2002 Aug 13;59(3):398-407. PubMed.

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