In testing the hypothesis that unscheduled cell death may alter APP processing, Andrea Le Blanc (122.4) provided compelling evidence that caspase 6 can directly cleave APP and cause an increase in Aβ levels in serum deprived human primary neurons. She is currently examining the p10 active fragment of caspase 6 in AD brain and non-AD age matched controls.—Dominic Walsh


No Available Comments

Make a Comment

To make a comment you must login or register.


No Available References

Further Reading

No Available Further Reading