Enabling Technologies for Alzheimer Disease Research: 2005 Bar Harbor Workshop

Bar Harbor, ME

07 – 10 September 2005

APP Function: A Report from Bar Harbor

In August 2005, a group of researchers from inside and outside the field of Alzheimer disease met in Bar Harbor, Maine, with foundation and NIH representatives for two days of presentations and discussion at the fifth annual workshop on Enabling Technologies for Alzheimer's Disease Research.

BBB/Brain Vasculature: A Report from Bar Harbor

After release, some Aβ is degraded locally, a second fraction leaves the brain through interstitial fluid drainage and along brain arterioles, while another fraction is actively transported by proteins, such as LRP and glycoprotein-P, across the blood-brain barrier (BBB) into systemic circulation.

Aging and AD: A Report from Bar Harbor

Clearly, the greatest risk factor for AD is advanced age, but a satisfying explanation of the link between aging and AD remains uncertain. To understand this connection, it is argued that a better understanding of "normal" aging is needed.

Enabling Technologies: A Report from Bar Harbor

This workshop has an enduring interest in facilitating the import into AD research of new technologies developed in other areas. This year an approach was presented that makes it possible to watch neurons grow and change over time inside living mice.