At Heidelberg meeting, scientists shared and debated new data on microglial function.
Instead of clearing plaques, do microglia seed them? The brain’s immune cells continue to take researchers by surprise.
At a conference in Heidelberg, researchers proposed that Aβ oligomers trigger local translation of tau in cytosol and dendrites, and that targeting this aberrant tau may preserve synapses.
Analysis of brain tissue from Alzheimer’s patients offers a glimpse of proteomic changes in the disease.
An astrocytic Aβ protease, destabilization of γ-secretase by FAD mutations, and an sAPP receptor all made their debuts at Heidelberg conference.