The Japanese research institute RIKEN has made several mouse models of Alzheimer’s disease more easily accessible. Amyloid precursor protein (APP) mutant knock-ins, APP x MAPT crosses, and mutant presenilin knock-ins are now available as open resources to not-for-profit institutions. RIKEN has simplified the agreements, and it no longer requires RIKEN scientists be listed as co-authors on initial publications that come from use of these animals. Mutant MAPT knock-ins will be made available once details of those mice are published.
For details, see comment from Takaomi Saido below.—Tom Fagan.
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