Technical Research Assistant ll


Brigham and Women’s Hospital – Neurology


Boston, Massachusetts

Principal Investigator

Dennis Selkoe


Working independently, under general supervision, executes protocols involving a variety of routine and non-routine experiments at a professional level. May identify new techniques. Develops modification of existing techniques, as appropriate. In close collaboration with other members of the research team, gives input to the development of immunoassay design protocols. Calculates, transcribes, and analyzes data using statistical techniques. May be responsible for orienting and training new staff. May serve in a supervisory role in the lab.


  1. Collects and interprets experimental data by using of a range of laboratory techniques such as:
    A. ELISA; immunoassay; biomarker screening; gel electrophoresis; immunoprecipitation; Western blotting; size exclusion chromatography, preparative ultracentrifugation, etc.
    B. Biochemical experiments on biological samples, including human CSF and plasma, and postmortem human brain tissue.
    C. Establishes and maintains cell lines, antibodies, immunoassay reagents, tissue culture supplies, equipment, etc.
  1. Uses judgment during experimental execution and meticulously performs procedures described laboratory protocols, research journals or devised with immediate supervisor.
  2. Helps to create a productive and professional work environment for self and other research personnel. 


  • Responsible for training and orienting new staff. 
  • May serve as a team leader or supervisor in a laboratory research setting.
Brigham and Women’s Hospital is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, color, religion, creed, sex, sexual orientation, gender identity, national origin, ancestry, age, veteran status, disability unrelated to job requirements, genetic information, military service, or other protected status. 



  • B.S. in biological/physical sciences or beyond.
  • Must have at least one-year post-baccalaureate experience in a related biological research setting.


  • Hands-on familiarity with biochemical and immunochemical methods.
  • High degree of computer literacy.
  • Sound analytical and organizational skills.
  • Requires good oral and written communication skills.
  • Ability to identify potential problems and trouble-shoot solutions.
  • Demonstrated ability to analyze biological data statistically and to logically present it.