Senior Scientific Researcher OMNI Biomarker Development (Neuroscience)
Posted 30 Mar 2021
South San Francisco, California
- Identify, develop, and qualify fit-for-purpose fluid biomarker assays for neurodegenerative diseases such as Alzheimer's disease.
- Evaluate biomarker assays in preclinical models, and optimize translatable assays for implementation in clinical trials.
- Collaborate with scientists and scientific researchers on cross-functional and inter-departmental teams to support the development and application of clinical biomarker strategies.
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- B.Sc. or M.Sc. with more than years of experience in biotechnology or academic research environments.
- Highly motivated, proactive, collaborative, creative, flexible, and scientifically curious.
- Ability to independently design, execute, and troubleshoot experiments.
- Attention to detail.
- Extensive experience in the development and qualification of immunoassays on a variety of platforms (e.g. ELISA, Simoa, Gyros, MSD, Singulex, Elecsys).
- Experience working with human samples and clinical biomarkers assays is desirable. Familiarity with blood and CSF biomarkers of Alzheimer’s Disease is a plus.
- An understanding of the drug development process and previous experience with regulatory documentation such as INDs and CTAs is desired but not required.
- Strong technical skills in the laboratory, with demonstrated excellence across a spectrum of laboratory techniques such as cell culture, cytometry, SDS-PAGE/immunoblotting, and qPCR.
- Experience with mass spectrometry is desirable but not required.
- Capacity and desire to monitor new technologies, evaluate novel biomarker assay platforms, and learn new methodologies quickly and thoroughly.
- Ability to independently analyze, interpret, organize, and communicate results.
- Experience and comfort with large datasets and basic statistics. Familiarity with MS Excel, MS Powerpoint, Tibco Spotfire, Graphpad Prism, and R.