Senior Director for Drug Development


Alzheimer's Drug Discovery Foundation


New York, New York

Principal Investigator

Howard Fillit


Please send a cover letter and resume to Jill Krumholz, Include “Senior Director for Drug Development” in the subject of the email. Only resumes with accompanying cover letters will be considered. No phone calls, please.


The senior director for drug development is a mid-career neuroscientist seeking to accelerate the development of late-stage preclinical and clinical-stage drug development for Alzheimer’s disease and related dementias. As part of a venture philanthropy that funds academic and biotechnology programs, this role will provide leadership, oversight and management to ADDF’s drug-development research portfolio and related strategic partnerships. The senior director for drug development will manage a team of neuroscientists and report directly to the founding executive director and chief science officer.

Key Responsibilities

  • Work with the chief science officer to provide strategic direction, program planning, progress oversight and attainment of shared goals and milestones of the ADDF late-stage preclinical drug discovery and clinical stage drug development (“core”) program.
  • Lead a team of ADDF neuroscientists dedicated to ADDF’s core program.
  • Provide thought leadership and management of the foundation’s portfolio of core programs for Alzheimer’s disease and related dementias.
  • Proactively search and identify promising academic and biotech investment opportunities, such as meeting with academic and biotechnology investigators, attending scientific conferences, mining scientific and patent literature, and connecting with key opinion leaders.
  • Provide guidance on due diligence and evaluation of academic and biotechnology core proposals.
  • Facilitate collaboration within the ADDF teams as well as ADDFs external partnership programs with other foundations, government and industry.
  • Facilitate the formation of interdisciplinary drug development teams through a network of ADDF consultants, collaborators, and partnerships.
  • As required, participate in the development and publication of peer-reviewed scientific publications, conference meeting reports, and other related core program materials for the foundation.

The position will require regular on-site availability post Covid-19.

Compensation will be commensurate with experience. A generous benefits package is included with compensation.

ADDF does not discriminate on the basis of race, color, national origin, sex, religion, age, disability, sexual orientation, gender identity, veteran status, height, weight, or marital status in employment or the provision of services and is an equal access/equal opportunity employer.


This position requires a Ph.D. or equivalent experience in a relevant biomedical discipline. The ideal candidate will have:

  • At least 10 years of drug discovery and clinical drug development experience in neuroscience or neurology from the pharmaceutical industry or a combination of industry and academia/nonprofit.
  • Experience in conceptualizing, designing, conducting, analyzing, and reporting clinical trials is required. A focus and receptiveness to scientific risk and innovative thinking will be an important asset.
  • Proven experience leading and motivating diverse teams of scientists and clinical trialists, and delivering high-quality data for preclinical and clinical studies.
  • Strong interpersonal skills and the ability to work closely and collaboratively with partner organizations, key opinion leaders, donors, and across all ADDF departments.
  • Excellent oral communications and writing skills with demonstrated ability to communicate to both scientific and lay audiences.
  • Exceptional project- and time-management skills with the ability to manage competing requests and shifting deadlines.