Senior Biostatistician


Massachusetts General Hospital


Boston, Massachustts


Description: If interested in this opportunity, please visit and apply for JOB ID#3223685

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Immediately available opportunity for a senior biostatistician to join the clinical trials program within the Harvard-MGH McCance Center for Brain Health. This individual will serve as the core statistician and leader on multiple projects, gain exposure to local, regional, national, and international collaborators, and have an opportunity for publications that shape our field.

Working closely with the clinical trials director, Gene Bowman, the senior biostatistician will be responsible for the following:

  • Composing statistical analysis plans for human investigations, including clinical trials and observational studies
  • Analysis of nutritional, genetic, and "omic" fluid biomarker data in relation to cognition, neuropathology, and neuroimaging outcomes
  • Develop/implement new and creative statistical approaches to the analysis of clinical trial and high-dimension data
  • Develop/implement new and creative data-capture approaches to streamline clinical research databases
  • Advise on study design, sample and power calculations, and ensure the integrity of randomization schemes in clinical trials
  • Contribute to Data and Safety Monitoring Board and Food and Drug Administration reports

WORKING CONDITIONS: Lab and office setting. Some travel may be required.



  • Experience with longitudinal and high-dimensional data in clinical trial settings
  • Experience through the publication of clinical trial designs; precision medicine approaches are an asset
  • Excellent verbal and written communication skills
  • Ability to follow through and timely reporting of results


  • Doctoral degree preferred


  • Minimum of five years of related experience required
  • At least two years of supervisory experience preferred

SUPERVISORY RESPONSIBILITY (authority to hire, promote, or terminate):

  • Direct: Management of one to three data analysts
  • Indirect: Provides support to investigators, who may also be directly analyzing data