Jobs

Scientist I, Neuroscience

Employer

Exicure, Inc.

Location

Skokie, Illinois

Contact

gcorbett@exicuretx.com

Description

Exicure, Inc. is seeking an experienced and independently motivated scientist to join its expanding preclinical neurology department. This dynamic position is suited for an individual who: i) possesses a strong background in preclinical in vitro and in vivo neurobiology, and ii) thrives in a fast-paced, team-oriented environment. The successful candidate will be responsible for executing and analyzing experiments as a member of a cross-disciplinary team focused on developing and advancing central nervous system (CNS) programs. Prior experience with nucleic acid therapeutics is preferred but not required.

Responsibilities:

  • Lead scientist on multiple preclinical CNS programs.
  • Design, execute, and interpret experiments centered around nucleic acid technologies.
  • Develop, validate and implement program-specific assays.
  • Build out induced pluripotent stem cell (iPSC)-derived neuronal cell culture platform.
  • Present data internally and at scientific conferences.
  • Function in a team environment by effectively collaborating within and across departments.

Requirements

  • Ph.D. in neuroscience (preferred), cellular biology, genetics, biochemistry, molecular biology or related field with up to two years of relevant experience.
  • Substantial experience with CNS dysfunction and/or neurodegeneration.
  • Substantial experience with iPSC and induced neuron biology generation, maintenance, and differentiation.
  • Strong expertise in mRNA and DNA isolation (cells/tissue) and quantification techniques.
  • Familiarity with various imaging techniques, including IHC and ICC.
  • Knowledge of antisense, siRNA or related therapeutic approaches is strongly preferred.
  • Experience with basic biochemical techniques, including western blot and ELISA.
  • Strong interpersonal skills as well as excellent communication and presentation abilities.