Research Technician I


The Alzheimer's Clinical & Translational Research Unit (ACTRU)


Boston, Massachusetts

Principal Investigator

Steven Arnold

Principal Investigator

Becky Carlyle


Please include a cover letter with your application detailing your specific interest in this position and how your previous experience relates to the principal duties of the role.


The Alzheimer's Clinical & Translational Research Unit (ACTRU) is seeking to hire a highly motivated and organized self-starter with excellent people skills to work with its rapidly expanding biomarkers operation. Work will be focused on running ELISA-based biomarker assays on three automated platforms in the lab, routine platform maintenance, and collaboration with academic and commercial collaborators to deliver high quality biomarker results in an optimal timescale.  Work will be performed under the supervision of the ACTRU research scientist responsible for biobanking and the co-director of the MGH Alzheimer’s Disease Research Center (MADRC) Biomarker Core. ACTRU is actively engaged in efforts to increase diversity both in our lab and in our clinical trials, and we encourage applications from under-epresented minorities and individuals aligned with these interests.


  • Run standardized ELISA assay protocols on the Tecan Evo200 Liquid handler platform, Fujirebio Lumipulse and Quanterix HD-X.  Direct experience with these specific platforms is not required, but candidate should be comfortable with running complex / robotic instrumentation.
  • Keep equipment in good working order and perform routine maintenance of all assay platforms (eg. daily washes, weekly cleaning etc.).
  • Monitor daily output from platforms for quality-control failures and consult with supervisors to address action to be taken for failed runs.
  • Learn basic programming of the Tecan Evo200 to adapt protocols to improve assay throughput and optimize workflows for individual studies.
  • Retrieval of samples from biorepository and sample preprocessing.
  • Follow standard lab procedures to perform quality-control testing of assays novel to this laboratory.
  • Follow Manuals of Operations (MOO) for standardized assay procedures and under supervision, develop new MOOs for incoming assays
  • Develop positive working relationships with the companies providing the instrumentation for quick resolution of issues that may arise with the platforms.
  • Participate in weekly lab meetings and present data.
  • Opportunities to travel and present at national conferences may be available at the discretion of the incumbent’s supervisor.
  • All other duties, as assigned.


  • Will assist PI with ordering using the electronic ordering system.

EEO Statement

Massachusetts General Hospital is an Equal Opportunity Employer.  By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.



  • Must be highly organized, detail-oriented, and have a strong motivation to learn.
  • Familiarity with ELISA assay principles.
  • Must be comfortable with the operation of complex instrumentation or robotic systems..
  • Prior programming experience (any scripting language).
  • Must have excellent interpersonal, speaking, and writing abilities.
  • Ability to manage work processes in a neat and orderly way, to follow instructions, and to work both independently and collaboratively as a member of a team.
  • Solid understanding of laboratory practices and procedures preferred.
  • On own initiative, ability to identify potential problems and troubleshoot problems as necessary.
  • Must be able to prioritize and perform multiple tasks independently.
  • Ability to demonstrate professionalism.
  • Sound degree of computer literacy required.


Minimum Required:

  •     High school diploma, GED or equivalent
  •     Certificate: Please specify
  •     Some college or Associate’s Degree
  •     X Bachelor’s Degree
  •     Master’s Degree
  •     Doctoral Degree
  •     None required


  •     High school diploma, GED or equivalent
  •     Certificate : Please specify
  •     Some college or Associate’s Degree
  •     Bachelor’s Degree
  •     Master’s Degree
  •     Doctoral Degree

Field of Study/Additional Specialized Training: Premedical sciences, bioengineering, or related science..


Preferred: Previous research experience desirable but not required.