Research Technician


The Alzheimer's Clinical & Translational Research Unit (ACTRU)


Boston, Massachusetts

Principal Investigator

Steven Arnold

Principal Investigator

Becky Carlyle


Please include a cover letter with your application detailing your specific interest in this position and how your previous experience relates to the principal duties of the role.


The Alzheimer's Clinical & Translational Research Unit (ACTRU) is seeking to hire a highly motivated and organized self-starter with excellent people skills to perform biomarker assays and associated biobanking activities.

This role will involve biomarker testing in our novel clinical trials, and support our roles as the biomarker cores for the Massachusetts Alzheimer’s Disease Research Center and Harvard Aging Brain studies. Work will be focused on developing ELISA based biomarker assays as fit for purpose, basic analysis of quality control metrics, and collaboration with the clinical team to streamline biomarker work flows. Work will be performed under the supervision of the co-director of the MGH Alzheimer’s Disease Research Center (MADRC) Biomarker Core and the ACTRU research scientist responsible for biobanking.

ACTRU is actively engaged in efforts to increase diversity both in its lab and in its clinical trials. Applications from under-epresented minorities and individuals aligned with these interests are encouraged.


  • Perform standardized ELISA and other biochemical assay protocols.
  • Perform fit-for-purpose assay testing according to the lab Manuals of Operation (MOO).
  • Under supervision from the co-director of the MADRC Biomarker Core, develop new MOOs for assays that pass fit-for-purpose testing.
  • Assess assay results for quality control failures and consult with supervisors to address action to be taken.
  • Collaborate closely with the ACTRU clinical team to streamline biomarker workflows and assist in sample collection and banking where necessary.
  • Retrieval of samples from biorepository and sample preprocessing.
  • Work with laboratory postdocs to support their sample preparation and routine experimental activities.
  • Participate in weekly lab meetings and present data.
  • Opportunities to travel and present at national conferences may be available at the discretion of the incumbent’s supervisor.
  • All other duties, as assigned.


  • Will assist PI with ordering using the electronic ordering system.

EEO Statement

Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.



  • Must be highly organized, detail-oriented, and have a strong motivation to learn.
  • Familiarity with ELISA assay principles.
  • Must have excellent interpersonal, speaking, and writing abilities.
  • Ability to manage work processes in a neat and orderly way, to follow instructions, and to work both independently and collaboratively as a member of a team.
  • Solid understanding of laboratory practices and procedures preferred.
  • On own initiative, ability to identify potential problems and troubleshoot problems as necessary.
  • Must be able to prioritize and perform multiple tasks independently.
  • Ability to demonstrate professionalism.
  • Sound degree of computer literacy required.


Minimum Required:

  •     High school diploma, GED or equivalent
  •     Certificate :  Please specify
  •     Some college or Associate’s Degree
  •     X Bachelor’s Degree
  •     Master’s Degree
  •     Doctoral Degree
  •     None required


  •     High school diploma, GED or equivalent
  •     Certificate : Please specify
  •     Some college or Associate’s Degree
  •     Bachelor’s Degree  
  •     Master’s Degree
  •     Doctoral Degree

Field of Study/Additional Specialized Training:  Premedical sciences, bioengineering, or related science.


Preferred: Previous research experience desirable but not required.