Research Lab Manager 1


Northwestern University


Chicago, Illinois


Northwestern University Opportunity (Job ID 37554):

Job Summary:

Manages daily operations of a research lab. Monitors lab performance, analyzes and reviews results, and supervises development and implementation of new protocols. Assigns work and supervises lab personnel and reviews technical operations, ensuring that all processes, protocols, and procedures are quality controlled and functioning up to standards. Develops implements, and administers budgets, grants, and administrative procedures. Co-authors scientific papers for presentation and publication and coordinates writing, submission, and administration of grants.

This individual will aid in the development of reagents and methods for quantitative methods in neurobiology including mass spectrometry, hyperspectral immunofluorescence microscopy, stereological methods and other methods such as ELISA and RNA-Seq. The candidate must have basic computer skills and be a good team player. The person selected for this position will assist in grant applications, data analyses, reporting, publication of laboratory findings, and presentation at conferences. They will also conduct independent experiments using brain preparations from research volunteers and experimental models.

Specific Responsibilities:

  • Manages technical operations of a lab involved in scientific research activities.
  • In consultation with Principle Investigator (PI), organizes and plans experiments ensuring those project objectives are attained.
  • Oversees and guides lab staff in review of results and recommendation of changes to protocols to improve validity and accuracy.
  • Conducts more complex experiments and analysis.
  • Using an advanced level of skill, completes the following activities (please highlight):

     Molecular Biology:

  • DNA, RNA, protein isolation, purification and expression
  • Southern, northern, western blotting
  • Plasmid preparation
  • Cloning, mapping and sequencing of DNA
  • Recombinant virus production and purification

Cellular Biology:

  • Cell culture, cell isolation
  • Functional studies
  • Transfection


  • Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining
  • Immunohistochemistry
  • Microscopy


  • Flow cytometry
  • ELISA, Elispot assay


  • Dissections


  • Immunofluorescence
  • Mass spectrometry
  • Stereology


  • Oversees and manages collection, maintenance, analysis, and evaluation of data that will be used in grant submissions, presentations and publications.
  • Ensures that information is entered correctly into databases.
  • Assists PI in reviewing, analyzing, interpreting, summarizing, formatting, editing, and preparing tables, charts, graphs, progress and final reports, etc.
  • Coordinates between sponsoring agencies, collaboration organizations and/or other research and/or educational institutions.
  • Ensures research regulations are adhered to, IRB and ACUC approvals in place, material transfer agreements properly executed, and that radiation and lab safety requirements are up to date and implemented.


  • Manages lab budget and inventory including purchasing of supplies and services ensuring that they are necessary, reasonable and project related.
  • Orders and maintains inventory of lab supplies, chemicals, equipment, and instrumentation and may distribute intradepartmental charges.
  • Negotiate with vendors, obtain quotes, and arrange for demos of large equipment.


  • Trains, directs, assigns duties to and supervises lab EEs, students, residents and/or fellows.
  • Provides instruction to lab users on technically complex procedures, equipment and instruments.
  • Typically manages a lab budget of $1,000,000-$3,000,000; 1,000-3,000 nasf of space and supervises 5-15 lab members.

For consideration, please click on the link below. For all resumes received, if there is interest in your candidacy, the human resources recruiter or the department hiring manager will contact you. Job Opening ID number for this position is 37554.

Current employees please use the following link instead:

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.


Minimum Qualifications:

  • Successful completion of a full four-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major or related; OR appropriate combination of education and experience and six years' lab/bench or other relevant experience required; OR
  • Successful completion of a full course of study in an accredited college or university leading to a master's or higher degree in a scientific major or related; OR appropriate combination of education and experience and four years' lab/bench or other relevant experience.
  • Supervisory or project management experience required.

Minimum Competencies: (Skills, knowledge, and abilities.)

  • Comprehensive understanding of scientific principles
  • General computer skills, experience with databases and scientific applications, and ability to quickly learn and master computer programs
  • Strong analytical skills and excellent judgment
  • Ability to work under deadlines with general guidance
  • Excellent organizational skills and demonstrated ability to complete detailed work accurately
  • Ability to work effectively with a team of scientists
  • Experience with microscopy and associated scientific protocols including antibody conjugations and slide staining (immunohistochemistry and immunofluorescence)

Preferred Qualifications:

  • Working with and publishing in neuroscience
  • Experience writing for research publications and/or reporting for research grants

Preferred Competencies: (Skills, knowledge, and abilities)

  • Experience with mass spectrometry platforms
  • Experience with antibody-based immuno-assays (ELISA, IP, bead-based assays)
  • Experience with stereological methods
  • Experience with high dimensional molecular assays such as RNA-Seq