Research Fellow (Postdoctoral Fellow)


Mayo Clinic Florida - Department of Neuroscience


Jacksonville, Florida

Principal Investigator

Sandro Da Mesquita


Please attach the following required documents at the time of application:

1. Current curriculum vitae and relevant bibliography

2. Three letters of recommendation, signed, on letterhead, describing:

  • Overall assessment of potential for success in research environment
  • Work qualities/personal conduct
  • Past work/academic performance
  • Relationship to the applicant

3. Ph.D. and/or M.D./Ph.D. degree certification: Original or notarized copy of diploma or final transcript issued by school (English translation required).


Research Fellow (postdoctoral) positions are available in the laboratory of Dr. Sandro Da Mesquita.

The Da Mesquita lab studies the meningeal lymphatic system in neurodegenerative disorders and is located in the Department of Neuroscience. The laboratory integrates several disciplines, techniques and state-of-the-art methodology to explore pathological mechanisms and biomarkers of aging-related neurological diseases like frontotemporal dementia, Alzheimer’s and Parkinson’s. Its main focus is to understand the roles of the recently described meningeal lymphatic system in modulating brain homeostasis, aging, pathology and degeneration, ultimately aiming at developing therapeutic strategies that promote brain cleansing and boost neural function in the aged brain by improving the drainage capacity of the meningeal lymphatic vasculature.

This opportunity is open to non-U.S. and U.S. resident scientists, including women, men, LGBTQI+, people with disabilities, and of all races, ethnicities, and underrepresented minorities.

Research fellowships at Mayo Clinic are temporary positions intended to provide postdoctoral training and education in research. Individuals will train in the research program of the Mayo Clinic Principal Investigator. Qualified individuals will demonstrate the potential for research as evidenced by their previous training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency might be required for J-1 Research Scholars sponsored by Mayo Clinic.


The lab seeks highly motivated individuals with a solid background in basic and/or translational research. The successful candidate will be a self-driven scientist, enjoying challenging research projects in a supportive diverse and multidisciplinary environment, and working in a timely, cordial, and ethical fashion with team members. The candidates will have to show a strong capacity of developing novel scientific concepts, ideas, and methods, alongside strong communication and presentation skills in English. Investigation will be conducted using in vivo models of human neurological disorders (mostly genetically engineered mice strains), as well as human tissue and biofluids.

In-depth knowledge about managing mice colonies and of in vivo techniques involving mouse models is mandatory. Previous experience with molecular and cellular biology techniques, state-of-the-art systems biology approaches (multi-omics) or behavioral testing will be major advantages. Proven capacity to set up in vitro models to answer specific research questions will also be considered. Understanding of basic concepts in the fields of neurovascular biology, neuroscience, neuroimmunology and/or immunology is an advantage. The candidate will also be expected to write manuscripts reporting research findings, originate novel, related, or follow-up research projects, and to participate in grant proposal writing to support the lab.