Project Scientist


University of California, Irvine, Institute for Memory Impairments and Neurological Disorders


Irvine, California


Please submit a letter of interest, curriculum vitae with a record of research experience, and the names of three references before May 15, 2018, to


The University of California, Irvine’s Institute for Memory Impairments and Neurological Disorders, has an opportunity for a project scientist position. This an opportunity to join the UCI Model Organism Development and Evaluation for Late-Onset Alzheimer’s Disease (MODEL-AD) Disease Modeling Project (DMP). MODEL-AD is an NIA/NIH-funded multiproject, multiinstitutional grant whose goal is to produce the next generation of mouse models for late-onset AD and develop new therapeutic targets. Under the direction of Grant MacGregor, professor and director of the UCI Transgenic Mouse Facility, the successful applicant will be responsible for leading daily operations of a large-scale project to generate improved mouse models of late-onset Alzheimer’s disease. The project involves use of contemporary methods of genome engineering in mice, combined with assisted reproduction and germplasm and preimplantation embryo cryopreservation. Other responsibilities include supervision of scientific research assistant(s) and student research assistant(s).

The University of California, Irvine, is an Equal Opportunity/Affirmative Action Employer committed to excellence through diversity. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.


Candidates with a doctoral degree in mouse developmental genetics and a minimum of 10 years experience in the field are encouraged to apply. Preference will be given to candidates with demonstrated experience in: mouse germplasm and embryo cryopreservation; in vitro fertilization using mouse germplasm; surgical transfer of preimplantation embryos to recipient mice; mouse breeding and husbandry, including C-section and fostering and development of PCR-based genotyping assays including TaqMan, rhAMP or similar fluorescent-probe-based assays, and the use of automated capillary electrophoresis. Eligible candidates should also have experience in genome analysis, database development and management, and strong record-keeping skills. Excellent supervisory skills, the ability to work independently, including setting team and personal goals and meeting deadlines and strong communication skills, are essential.